李志鹏导师简介

个人简介：

李志鹏，男，1982年12月出生，毕业于北京协和医学院。博士，教授，山西中医药大学博士生导师。先后主持国家自然科学基金面上项目、省自然科学基金面上项目等科研项目10余项，以第一或通讯作者发表SCI论文30余篇，参编学术著作2部。

研究学科（领域）：中药药理学

研究方向：中药抗代谢疾病与神经精神疾病药理研究

在研项目：

1.山西中医药大学人才引进启动经费，2025.09-2029.12，100万元，主持

2.葛根素保护炎症损伤胰岛β细胞的作用机制研究，2025年度山西省回国科教创新资助项目，2025.12-2028.12，3万元，主持

代表性成果：

1. Zhang ZH, Sun LY, Guo YP, Zhao J, Li JQ, Pan XH, Li ZP*. Bavachin ameliorates neuroinflammation and depressive-like behaviors in streptozotocin-induced diabetic mice through the inhibition of PKCδ. Free Radical Biology and Medicine, 2024, 213:52-64

2. Guo YP, Xu S, Pan XH, Xin WY, Cao WL, Ma WY, Li L, Shen Q*, Li ZP*. Psoralen protects neurons and alleviates neuroinflammation by regulating microglial M1/M2 polarization via inhibition of the Fyn-PKCδ pathway. International Immunopharmacology 2024, 137:112493

3. Zhang X, Guo YP, Zhang ZH, Wu XT, Li L, Yang ZP*, Li ZP*. Neuroprotective effects of bavachin against neuroinflammation and oxidative stress-induced neuronal damage via activation of Sirt1/Nrf2 pathway and inhibition of NF-κB pathway. Journal of Functional Foods 2023, 107: 105655

4. Wu XT, Zhang ZH, Zhang X, Guo YP, Liu F, Gong JW, Li L, Chen XY*, Li ZP*. Upregulation of A20 and TAX1BP1 contributes to the anti-neuroinflammatory and antidepressant effects of bavachalcone. International Immunopharmacology 2023, 122: 110552

5. Li ZP*, Chu SF, He WB, Zhang Z, Liu JQ, Cui LY, Yan X, Li DF*, Chen NH*. A20 as a novel target for the anti-neuroinflammatory effect of chrysin via inhibition of NF-κB signaling pathway. Brain, Behavior, and Immunity, 2019, 79:228-235

联系方式：

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