秦雪梅导师简介
个人简介：
秦雪梅，女，1964年1月出生，毕业于山西大学。博士，教授，山西中医药大学博士生导师，山西大学硕士生导师，博士生导师。山西中医药大学太行本草研究院执行院长。先后主持科研项目40余项，发表论文630余篇，其中SCI论文120余篇，出版专著8部。
在研项目：
1.黄芪功效多样性的活性物质相态特征及质量关联性研究（U23A20517），国家自然科学基金委员会，区域联合项目，2024.01-2027.12，258万元，主持
2.治疗老年性肌少症医疗机构创新中药制剂研发（2024kjzy002），山西省科技厅，中医药科技创新工程项目，2024.01-2026.12，235万元，主持
3.逍遥散调节抑郁症葡萄糖分解代谢异常通路的稳定同位素示踪代谢组学探讨（82074147），国家自然科学基金委员会，面上项目，2021.01-2024.12，55万元，主持
代表性成果：
代表性论文：
1.Yuetao Liu#, Xu Lian, Xuemei Qin#. Bile acid metabolism involved into the therapeutic action of Xiaojianzhong Tang via gut microbiota to treat chronic atrophic gastritis in rats. Phytomedicine, 2023, 109: 154557.
2.Qi Wang, Zhenning Wu, Huan Xiang, Yuzhi Zhou#, Xuemei Qin#, Junsheng Tian#. Revealing the role of leucine in improving the social avoidance behavior of depression through a combination of untargeted and targeted metabolomics. Food Funct, 2023, 14(14): 6397-6409.
3.Rui Wei, Xuemei Qin#, Zhenyu Li#. Comparison of the inedible parts of white and green asparagus based on metabolomics and network pharmacology, Food Funct, 2023, 14: 7478-7488.
4.Xiaojie Liu, Chen Jian, Mengyu Li, Xuemei Qin#. Microbiome-metabolomics deciphers the effects of Cistanche deserticola polysaccharides on aged constipated rats. Food Funct, 2022, 13(7): 3993-4008.
5.Wenze Wu, Ting Ling-Hu, Yunhao Zhao, Junsheng Tian#, Yan Ren#, Xuemei Qin#. A unique insight for Xiaoyao San exerts antidepressant effects by modulating hippocampal glucose catabolism using stable isotope-resolved metabolomics. J Ethnopharmacol, 2023, 300: 115702.
6.Aiping Li, Wenbo Cui, Yirui Zhao, Xuemei Qin#, Lichao Zhang#. Exploration of the main effective constituent and the mechanism in Astragali Radix in the treatment for doxorubicin-induced nephropathy by integrating metabolomics and molecular docking. J Ethnopharmacol, 2023, 305: 116074.
7.Renjie Ding, Suyun Ning, Xiaoling Yang, Xiaoxia Gao#, Xuemei Qin#. Brain and testicular metabonomics revealed the protective effects of Guilingji on senile sexual dysfunction rats. J Ethnopharmacol, 2022, 290: 115047.
8.Junsheng Tian, Yunhao Zhao, Ting Ling-Hu, Xuemei Qin#. A novel insight for high-rate and low-efficiency glucose metabolism in depression through stable isotope-resolved metabolomics in CUMS-induced rats. J Affect Disord, 2023, 331: 121-129.
9.Yuetao Liu#, Yudie Liu, Jing Hu, Xuemei Qin#. Integration of diagnostic ions, molecular network and chemometrics to illustrate the chemical mechanism of Radix Astragali processed with honey. J Chromatogr A, 2023, 1709: 464381.
10.Junsheng Tian, Wenze Wu, Shaobo Liu, Xuemei Qin#. Stable Isotope-Resolved Metabolomics Studies on Corticosteroid-Induced PC12 Cells: A Strategy for Evaluating Glucose Catabolism in an in Vitro Model of Depression. J Proteome Res, 2022, 21(3): 788-797.
授权专利：
1.秦雪梅，杨柳，李爱平，张王宁，张丽增.肾病综合征病变进程相关代谢标志物及其应用，2021-9-28，中国，ZL201910509827.8.
2.令狐婷，秦雪梅，田俊生，高耀，张丽增.一种基于稳定同位素示踪代谢组学鉴定抑郁症能量代谢异常通路的方法，2022-3-18，中国，ZL202010535066.6.
3.高耀，秦雪梅，田俊生，令狐婷.一种生物标志物代谢通路及分析方法与应用，2021-7-27，中国，ZL201910567765.6.
学术奖励：
1.秦雪梅（1/8），逍遥散抗抑郁作用及其代谢组学机制研究与应用，山西省科技厅，山西省科技进步，二等奖，2020
2.秦雪梅（2/5），基于代谢组学技术的中药质量评价研究与应用，山西省科技厅，山西省科技进步，二等奖，2021
学术专著：
1.秦雪梅，柴胡及解郁方剂研究，化学工业出版社，ISBN：978-7-122-40627-9
联系方式：
办公电话：0351-7018379
Email：qinxm@sxu.edu.cn
