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尚楠

发布者: [发表时间]:2025-10-15 [来源]: [浏览次数]:

尚楠导师简介

个人简介:

尚楠19863月出生,毕业于山西医科大学。博士,副主任药师,山西中医药大学硕士生导师。先后主持科研项目  9项,发表论文17余篇,其中SCI论文10篇,中文核心6篇,出版专著2余部。

研究学科(领域):中药药理学

研究方向:中药药理学

在研项目

  1. Rhoa/Rock 调控Mfsd2a泛素化在铝与PFAS联合暴露降低职业人群认知功能中的机制研究(编号:2024-146),山西省教育厅省筹资金资助回国留学人员科研项目,2024.06-2027.06,在研,主持,6万。

  2. 健康中国山西行动视角下我省阿尔兹海默症患者的流行病学现状分析(编号:DJKZXKT2023094),山西省大健康产业高质量发展科研专项课题,2024.01-2024.12,在研,主持0.5万

  3. 铝致认知功能障碍的蛋白组联合代谢组共富集通路分析 (编号:20230048),山西省人社厅,山西省留学人员科技活动项目,2023.03-2025.03,在研,主持,5万元。

  4. 龟龄集调控血脑屏障昼夜节律对轻度认知功能障碍改善作用的机制研究(编号:2024ZYY2B041),山西省中医药科研课题,2024.11-2027.11,在研,主持,2万元。

  5. 微生物菌群在 PI3K/Akt/mTOR 介导的铝锌联合暴露致认知障碍中的改变研究(编号:20210302124090), 山西省科学技术厅, 青年科学研究项目,2022.01- 2024.12,在研,主持,5 万元

  6. 铝暴露致认知障碍与肠道菌群相关性研究,山西省教育厅,编号:2021L183,2021.12-2023.11,在研,主持,2万元

代表性成果:

  1. Li, X., Yue, X., Zhang, L., Zheng, X., & Shang, N. Pharmacist-Led Surgical Medicines Prescription Optimization and Prediction Service Improves Patient Outcomes-A Machine Learning Based Study. Frontiers in Pharmacology, 16, 1534552.

  2. Nan Shang, Xianlin Li, Guo, Zhiyu, Lan Zhang, Shanshan Wang. Comparative analysis of the safety and effectiveness of Nirmatrelvir-Ritonavir and Azvudine in elderly patients with COVID-19: a study from a tertiary hospital in China.Frontiers in Pharmacology, 2024, 15: 1362345.

  3. Shang, N., Li, X., Zhang, L., Wang, S., He, C., Zhang, L., Niu, Q., Zheng, X. Zinc as a Mediator Through the ROCK1 Pathway of Cognitive Impairment in Aluminum-Exposed Workers: A Clinical and Animal Study. Biological Trace Element Research, 2024: 1-16.

  4. Luan, S., Li, R., Li, Q., Zhang, X., Jin, Y., Wang, Y., & Shang, N. Development and Application of a Comprehensive Hospital Pharmacy Service Assessment Model Using Principal Component Analysis[J]. Research in Social and Administrative Pharmacy, 2024.

  5. Nan Shang, Lan Zhang, Qi Gao, Weipeng Li, Shanshan Wang, Xiaocheng Gao, Jin Chen, Ling Zhang, Qiao Niu, Qinli Zhang, Simultaneous effects of aluminum exposure on the homeostasis of essential metal content in rat brain and perturbation of gut microbiota,Ecotoxicology and Environmental Safety, Volume 254, 2023, 114707.

  6. Nan Shang, Lan Zhang, Shuo Wang, Tao Huang, Yanhong Wang, et al.Increased of Aluminum, Lithium and decreased of Zinc in plasma is related to Cognitive Impairment in Workers at an Aluminum Factory in China: A Cross-sectional Study. Ecotoxicology and Environmental Safety. 2021.214.112110.

  7. Shang, N., Liu, Y. and Jin, Y. (2024) ‘Comparative Efficacy of Budesonide/Formoterol Versus Fluticasone/Salmeterol in Patients With Moderate-to-Severe Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis’, COPD: Journal of Chronic Obstructive Pulmonary Disease, 2024, 21(1): 2328708.

  8. Li, X., Shang, N., Yan, Q., Yue, X., Liu, Y., & Zheng, X. (2024). Investigating bleeding adverse events associated with BTK inhibitors in the Food and Drug Administration adverse event reporting system (FAERS). Expert Opinion on Drug Safety. https://doi.org/10.1080/14740338.2024.2339448

  9. Nan Shang, Ping Zhang, Shuo Wang, Jianping Chen, Rong Fan, et al. Aluminum-Induced Cognitive Impairment and PI3K/Akt/mTOR signaling pathway involvement in Occupational aluminum workers. Neurotox Res. 2020:382(2):344-358.

  10. Shang N, Zhang J, Shao B. Simultaneous determination of azoles antifungaldrugs in chicken tissues by ultra-performance liquid chromatography tandem massspectrometry. Anal Sci., 2013,29(12):1183-8.

  11. 赵婧媛, 刘洋, 尚楠. 1990至2021年中国职业性多环芳烃暴露相关性肺癌的潜在疾病负担分析[J]. 中华劳动卫生职业病杂志, 2025, 43(06): 431-434. DOI: 10.3760/cma.j.cn121094-20240912-00428

  12. 樊丽娟,张智琪,程晓军,岳秀楠,成海燕,尚楠.机器学习辅助处方合理性预测模型在围手术期合理用药管理中的应用[J]. 药物流行病学杂志,2024, 33(11):1219-1228.DOI: 10.12173/j.issn.1005-0698.202409026.  

  13. 尚楠,张勤丽,候美娟,张欣,田杰,王燕,晋月萍.药物神经发育毒性比较及筛查模型建立.中国医院药学杂志,2020,40(7):777-782.

  14. 尚楠,王硕,王姗姗, 等.铝作业工人血液中铝测定的ICP-MS法[J].中华劳动卫生职业病杂志,2019,37(7):541-544.

  15. 尚楠, 贺凯宏, 张萍, 等. 铝致神经细胞程序性死亡通路对铝作业工人认知功能的影响: 2017环境与公共健康学术会议暨中国环境科学学会环境医学与健康分会、中国毒理学会生化与分子毒理专业委员会2017年年会, 中国广东广州, 2017[C].

  16. 尚楠, 朱珠, 李青. 从我国医疗机构退药文献看住院退药的隐性成本[J]. 中国医院药学杂志, 2015,35(7): 633-639.

  17. 尚楠,郭娟,张银,王浩,张晶,李青山,邵兵. 噻苯哒唑及其代谢产物在蛋鸡体内的残留分布及消除研究[J]. 卫生研究,2011,03:365-367+374.

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