周静导师简介

个人简介:
周静,女,1989年1月出生,毕业于中南大学。博士,副主任医师,湖南省2018届优秀博士毕业生,山西省“三晋英才”支持计划青年优秀人才,第五批山西省中青年中医临床优秀骨干,北京大学医学部访问学者,国自然项目函审专家。中华中医药学会名医学术研究分会委员;中国微循环学会转化医学专业委员会循环肿瘤细胞学工作委员会青年委员;山西省老年学和老年健康学会中西医结合专业委员会委员;山西省老年和老年健康学会中西医结合肿瘤多学科专业委员会常务委员;中国抗癌协会中西医整合泌尿肿瘤专委会委员。近五年主持科研项目12项,发表论文10余篇,其中SCI论文14篇,出版专著1部。目前指导硕士研究生2人。
研究学科(领域):中医内科学
研究方向:中医药防治肿瘤疾病的研究
在研项目:
(1)基于“TAMs极化重编辑诱导血管正常化”探究软坚散结胶囊抗脑胶质廇的作用与机制(81904183),国家自然科学基金青年基金项目, 2020.01-2022.12,20万元,主持。
(2) 基于外泌体miR-126/MerTK-胞葬途径的软坚散结胶囊重塑脑胶质瘤免疫微环境的机制研究(82274498),国家自然科学基金面上基金项目,2023.01-2026.12,52万元,主持
(3) 脑胶质瘤病理机制研究及中药新药、纳米制剂研发(202304051001046),山西省科技厅科技创新人才团队项目,2023.8.31- 2026.8.31,50万元,主持
(4)抗脑胶质瘤中药复方、中药碳纳米点制剂研发及应用传承创新团队(zyytd2024007), 山西省卫健委中医药传承创新培育团队项目, 2024.3-2027.3, 30万元,主持
(5)软坚散结胶囊促进脑胶质瘤血管正常化增强TMZ疗效的作用及机制研究(2022XM36),山西省医学重点科研项目(四个一批),2022.09-2024.08,15万,主持。
(6)靶向CDCA5的软坚散结胶囊抗脑胶质瘤作用及机制研究(2022082),山西省卫健委科研项目,2022.01-2023.12,3万元,主持。
代表性成果:
Zhou J, Guo H, Liu LK, et al. Construction of co-expression modules related to survival by WGCNA and identification of potential prognostic biomarkers in glioblastoma. J Cell Mol Med.2021;25(3): 1633-1644.
Zhou J, Guo H, Liu LK, et al.Identification of immune-related hub genes and construction of an immune-related gene prognostic index for low-grade glioma. J Cell Mol Med. 2023;27(23):3851- 3863.
Zhang WC, Wang Ying, Zhou J(通讯作者), et al. Exploring the mechanism of Erteng-Sanjie capsule in treating gastric and colorectal cancers via network pharmacology and in-vivo validation. J Ethnopharmacol. 2024;327:117945.
(4) Zhou J, Li YC, Shi XJ, et al. Oridonin inhibits tumor angiogenesis and induces vessel normalization in experimental colon cancer. Journal of cancer. 2021; 12(11): 3257-3264.
(5) Zhou J, Zheng J, Zhang Y, et al. Chitosan Hydrogel Delivery System Containing Herbal Compound Functions as a Potential Antineuroinflammatory Agent. ACS Omega, 2019, 4:10185-10191.
(6) Guo H, Zhou J (通讯作者), Zhang YJ, et al. Identification hypoxia-related differentially expressed genes and construction the clinical progn ostic predictor in hepatocellular carcinoma by bioinformatic analysis. Bio Res Inter. 2021;2021.
(7) Zhou J,Erteng Sanjie capsule enhanced the chemosensitivity of 5-FU in tumor-bearing nude mice with gastric cancer by inhibiting Notch1/Hes1 signaling pathway. Evidence-Based Com Alt Med.2021
(8) Zhou J, Shi XJ, Li YC, et al. Case report of pulmonary metastasis in a male Wistar rat glioblastoma model. J Toxicol Pathol. 2021; 34(1): 95–9 9.
(9) Guo Z, Zhou J(通讯作者), Guo H, Liu LK. Radiotherapy- induced abscopal effect on the metastatic carcinoma of unknown primary origin: a case report and literature review. EUR REV MED PHARMACO. 2022;26(13):4634-4637.
(10) Zhou J, Guo H, Liu LK, et al. Pyroptosis pattern of colon cancer could aid to estimate prognosis, microenvironment and immunotherapy: evidence from multi-omics analysis. Aging-US. 2022, 14(18): 7547-7567.
联系方式:
办公电话:0351-4668162
E-mail: zhoujingsx07@163.com