闫玉清导师简介

个人简介：

闫玉清，女，1964年5月出生，毕业于哈尔滨师范大学。博士，多伦多病童医院博士后，教授，山西中医药大学硕士生导师。先后主持科研项目10项，国内外发表论文30余篇，其中中文核心（或SCI）论文第一及通讯作者多篇，主编生物技术制药书一部，主持项目获市科技进步一等奖和省优秀新产品开发奖一等奖各1项。

研究学科（领域）：神经病学

研究方向：神经系统变性疾病及药物治疗机制的研究 

在研项目：

1. Rho激酶抑制剂Fasudil抗凋亡治疗阿尔兹海默症（AD）的研究 （201803D421073），山西省科技厅国际合作项目， 201812-202012

2.神经变性疾病生物技术平台建设（2019198），大同市平台重点研发计划项目，201908-202112

3.Fasudil 对于阿尔兹海默症的治疗作用及其脑肠轴机制—基于外泌体研究（20210302124315），山西省科技厅基础研究计划（自由探索类）项目，2022.01-2025.01 

代表性成果：

1. Hailong Yan, Yuqing Yan, et al. (Corresponding author and contributed equally with first author). Transcriptome Analysis of Fasudil Treatment in the APPswe/PSEN1dE9 transgenic (APP/PS1) mice Model of Alzheimer’s Disease. Scientific Reports. 2022.

2. Yuqing Yan, Gao Y, et al. Inhibition of Rho Kinase by Fasudil Ameliorates Cognition Impairment in APP/PS1 Transgenic Mice via Modulation of Gut Microbiota and Metabolites[J]. Frontiers in Aging Neuroscience, 2021: 649.

3. Ye Gao, Yuqing Yan, et al. (Corresponding author and contributed equally with first author). The Rho kinase inhibitor fasudil attenuates Aβ1-42-induced apoptosis via the ASK1/JNK signal pathway in primary cultures of hippocampal neurons. Metabolic Brain Disease. 2019, 34(6):1787-1801.

4. Yuqing Yan, Jiezhong Yu, et al. Therapeutic potentials of the Rho kinase inhibitor Fasudil in experimental autoimmune encephalomyelitis and the related mechanisms. Metabolic Brain Disease. 2019, 34(2) : 377-384.

5. Jiezhong Yu, Yuqing Yan, et al. (Contributed equally with first author). Fasudil in Combination With Bone Marrow Stromal Cells (BMSCs) Attenuates Alzheimer’s Disease-Related Changes Through the Regulation of the Peripheral Immune System. Frontiers in Aging Neuroscience. 2018, 10 (216) : 1-9.

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